Description
Product Overview
MOTS-c is a synthetic 16-amino-acid mitochondrial-derived peptide supplied for laboratory research use only.
Published scientific literature has investigated MOTS-c in relation to mitochondrial-derived peptide biology, mitochondrial-nuclear signaling, cellular stress response and metabolic research models.
Technical Specifications
- Product Name: MOTS-c
- Product Type: Synthetic Mitochondrial-Derived Peptide
- Amount: 10 mg / 40 mg
- Form: Lyophilized Powder
- Purity: ≥99%
- Storage: 2–8°C
- Batch Testing: Batch-Specific COA Available
- Intended Use: Research Use Only
Batch Verification
Each batch is linked to a batch-specific Certificate of Analysis (COA).
Available documentation may include purity testing, identity verification, and batch-related analytical data.
Selected Scientific References
Lee C, Zeng J, Drew BG, Sallam T, Martin-Montalvo A, Wan J, Kim SJ, Mehta H, Hevener AL, de Cabo R, Cohen P.
The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance.
Cell Metabolism. 2015;21(3):443–454.
PMID: 25738459
DOI: 10.1016/j.cmet.2015.02.009
Kim KH, Son JM, Benayoun BA, Lee C.
The mitochondrial-encoded peptide MOTS-c translocates to the nucleus to regulate nuclear gene expression in response to metabolic stress.
Cell Metabolism. 2018;28(3):516–524.e7.
PMID: 29983246
DOI: 10.1016/j.cmet.2018.06.008
Reynolds JC, Lai RW, Woodhead JST, Joly JH, Mitchell CJ, Cameron-Smith D, Lu R, Cohen P, Graham NA, Benayoun BA, Merry TL, Lee C.
MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis.
Nature Communications. 2021;12(1):470.
PMID: 33473109
DOI: 10.1038/s41467-020-20790-0
Wan W, Zhang L, Lin Y, Rao X, Wang X, Hua F, Ying J.
Mitochondria-derived peptide MOTS-c: effects and mechanisms related to stress, metabolism and aging.
Journal of Translational Medicine. 2023;21(1):36.
PMID: 36670507
DOI: 10.1186/s12967-023-03885-2
Research Profile
- Product Name: MOTS-c
- Product Type: Synthetic Mitochondrial-Derived Peptide
- Amount: 10 mg / 40 mg
- Form: Lyophilized Powder
- Purity: ≥99%
- Storage: 2–8°C
- Batch Testing: Batch-Specific COA Available
- Intended Use: Research Use Only
Scope of Use
This product is supplied strictly for laboratory research purposes.
It is not intended for human use, veterinary use, diagnostic applications, or therapeutic and clinical applications.
True Peptides does not provide dosing guidance, administration instructions, or usage recommendations.




