Description
Product Overview
5-Amino-1MQ is a small-molecule nicotinamide N-methyltransferase (NNMT) inhibitor supplied for laboratory research use only.
Published scientific literature has investigated 5-Amino-1MQ and NNMT inhibition in relation to nicotinamide metabolism, methyltransferase biology and cellular metabolism research models.
Technical Specifications
- Product Name: 5-Amino-1MQ
- Product Type: Small-Molecule NNMT Inhibitor
- Amount: 51000 mg
- Form: Powder
- Purity: ≥99%
- Storage: 2–8°C
- Batch Testing: Batch-Specific COA Available
- Intended Use: Research Use Only
Batch Verification
Each batch is linked to a batch-specific Certificate of Analysis (COA).
Available documentation may include purity testing, identity verification, and batch-related analytical data.
Selected Scientific References
Kraus D, Yang Q, Kong D, Banks AS, Zhang L, Rodgers JT, et al.
Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity.
Nature. 2014;508(7495):258–262.
PMID: 24717514
DOI: 10.1038/nature13198
Neelakantan H, Vance V, Wetzel MD, Wang HYL, McHardy SF, Finnerty CC, et al.
Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice.
Biochemical Pharmacology. 2018;147:141–152.
PMID: 29155147
DOI: 10.1016/j.bcp.2017.11.007
Awosemo O, Neelakantan H, Watowich S, Ma J, Wu L, Chow DS, et al.
Development & validation of LC-MS/MS assay for 5-amino-1-methyl quinolinium in rat plasma: Application to pharmacokinetic and oral bioavailability studies.
Journal of Pharmaceutical and Biomedical Analysis. 2021;204:114255.
PMID: 34304009
DOI: 10.1016/j.jpba.2021.114255
Babula JJ, Bui D, Stevenson HL, Watowich SJ, Neelakantan H.
Nicotinamide N-methyltransferase inhibition mitigates obesity-related metabolic dysfunction.
Diabetes, Obesity and Metabolism. 2024;26(11):5272–5282.
PMID: 39161060
DOI: 10.1111/dom.15879
Research Profile
- Product Name: 5-Amino-1MQ
- Product Type: Small-Molecule NNMT Inhibitor
- Amount: 1000 mg
- Form: Powder
- Purity: ≥99%
- Storage: 2–8°C
- Batch Testing: Batch-Specific COA Available
- Intended Use: Research Use Only
Scope of Use
This product is supplied strictly for laboratory research purposes.
It is not intended for human use, veterinary use, diagnostic applications, or therapeutic and clinical applications.
True Peptides does not provide dosing guidance, administration instructions, or usage recommendations.





